LDHB antibody

Catalog No. ABIN5647182

Product Details anti-LDHB Antibody

Target: LDHB (Lactate Dehydrogenase B (LDHB))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LDHB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity purified

Immunogen: Amino acids E237-L334 from the human protein were used as the immunogen for the LDHB antibody.

Isotype: IgG

Application Details

Application Notes: Western blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the LDHB antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for LDHB

Target: LDHB (Lactate Dehydrogenase B (LDHB))

Alternative Name: LDHB / Lactate dehydrogenase B (LDHB Products)

Synonyms: LDH-B antibody, LDH-H antibody, LDHBD antibody, TRG-5 antibody, AI790582 antibody, H-Ldh antibody, Ldh-2 antibody, Ldh2 antibody, ldh-h antibody, ldh2 antibody, ldhb antibody, ldhba antibody, trg-5 antibody, LDHB antibody, LDH-B-A antibody, wu:fa16d07 antibody, wu:fa20c10 antibody, wu:fa96a08 antibody, LDH-B-B antibody, zgc:92882 antibody, lactate dehydrogenase B antibody, lactate dehydrogenase B S homeolog antibody, lactate dehydrogenase Ba antibody, lactate dehydrogenase Bb antibody, LDHB antibody, Ldhb antibody, ldhb.S antibody, ldhb antibody, ldhba antibody, ldhbb antibody

Background: The LDHB gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13.

UniProt: P07195

Pathways: Warburg Effect