HSD17B4 antibody

Catalog No. ABIN5647728

Product Details anti-HSD17B4 Antibody

Target: HSD17B4 (Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSD17B4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity purified

Immunogen: Amino acids D510-L736 from the human protein were used as the immunogen for the HSD17B4 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the HSD17B4 antibody should be determined by the researcher.\. WB: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the HSD17B4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for HSD17B4

Target: HSD17B4 (Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4))

Alternative Name: 17-beta-Hydroxysteroid dehydrogenase 4 (HSD17B4) (HSD17B4 Products)

Synonyms: zgc:55545 antibody, zgc:77300 antibody, CG3415 antibody, DmMFE-2 antibody, Dmel\\CG3415 antibody, MFE-2 antibody, DBP antibody, MPF-2 antibody, PRLTS1 antibody, SDR8C1 antibody, 17-beta-HSD antibody, 17[b]-HSD antibody, 4 antibody, MFP2 antibody, Mfp-2 antibody, perMFE-2 antibody, hydroxysteroid (17-beta) dehydrogenase 4 antibody, hydroxysteroid 17-beta dehydrogenase 4 antibody, peroxisomal Multifunctional enzyme type 2 antibody, hsd17b4 antibody, HSD17B4 antibody, Mfe2 antibody, Hsd17b4 antibody

Background: Peroxisomal multifunctional enzyme type 2 is a protein that in humans is encoded by the HSD17B4 gene. The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

UniProt: P51659

Pathways: Monocarboxylic Acid Catabolic Process