Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

HSD17B4 Products

(Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4))

Categories

The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. [provided by RefSeq, Jul 2008].

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured HSD17B4 Categories

HSD17B4 Antibodies

High quality antibodies with extensive validation data.

HSD17B4 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HSD17B4 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Rat
Application ICC, IF, IHC (p), WB
Validations
  • (1)
  • (5)
Cat. No. ABIN2855717
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC (p), WB
Validations
  • (5)
Cat. No. ABIN3031274
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application ICC, IF, IHC (p), WB
Validations
  • (4)
Cat. No. ABIN2856979
Quantity 100 μL
Datasheet Datasheet

Recommended HSD17B4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3078926
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3078927
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3134368
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our HSD17B4 products

Eun, Lee, Nam, Liu, So, Choe, Park: "PEX5 regulates autophagy via the mTORC1-TFEB axis during starvation." in: Experimental & molecular medicine, Vol. 50, Issue 4, pp. 4, (2019) (PubMed).

Zhu, Chen, Wang, Elsherbini, Zhong, Jiang, Qin, Tripathi, Zhi, Spassieva, Morris, Bieberich: "Ceramide regulates interaction of Hsd17b4 with Pex5 and function of peroxisomes." in: Biochimica et biophysica acta. Molecular and cell biology of lipids, Vol. 1864, Issue 10, pp. 1514-1524, (2019) (PubMed).

Dávalos-Salas, Montgomery, Reehorst, Nightingale, Ng, Anderton, Al-Obaidi, Lesmana, Scott, Ioannidis, Kalra, Keerthikumar, Tögel, Rigopoulos, Gong, Williams, Yoganantharaja, Bell-Anderson, Mathivanan et al.: "Deletion of intestinal Hdac3 remodels the lipidome of enterocytes and protects mice from diet-induced obesity. ..." in: Nature communications, Vol. 10, Issue 1, pp. 5291, (2019) (PubMed).

Zhang, Zhao, Zhang, Hao, Yu, Min, Li, Ma, Chen, Yi, Tang, Meng, Liu, Wang, Shen, Zhang: "Decrease in male mouse fertility by hydrogen sulfide and/or ammonia can Be inheritable." in: Chemosphere, Vol. 194, pp. 147-157, (2018) (PubMed).

Maier, Luks, Baudendistel, Wittmann, Dietrich: "Identification of d-amino acid oxidase and propiverine interaction partners and their potential role in the propiverine-mediated nephropathy." in: Chemico-biological interactions, Vol. 281, pp. 69-80, (2018) (PubMed).

Frasinyuk, Zhang, Wyrebek, Yu, Xu, Sviripa, Bondarenko, Xie, Ngo, Morris, Mohler, Fiandalo, Watt, Liu: "Developing antineoplastic agents that target peroxisomal enzymes: cytisine-linked isoflavonoids as inhibitors of hydroxysteroid 17-beta-dehydrogenase-4 (HSD17B4)." in: Organic & biomolecular chemistry, Vol. 15, Issue 36, pp. 7623-7629, (2018) (PubMed).

Naudí, Cabré, Dominguez-Gonzalez, Ayala, Jové, Mota-Martorell, Piñol-Ripoll, Gil-Villar, Rué, Portero-Otín, Ferrer, Pamplona: "Region-specific vulnerability to lipid peroxidation and evidence of neuronal mechanisms for polyunsaturated fatty acid biosynthesis in the healthy adult human central nervous system." in: Biochimica et biophysica acta, Vol. 1862, Issue 5, pp. 485-495, (2017) (PubMed).

Cabré, Naudí, Dominguez-Gonzalez, Jové, Ayala, Mota-Martorell, Pradas, Nogueras, Rué, Portero-Otín, Ferrer, Pamplona: "Lipid Profile in Human Frontal Cortex is Sustained Throughout Healthy Adult Lifespan to Decay at Advanced Ages." in: The journals of gerontology. Series A, Biological sciences and medical sciences (PubMed).

Synonyms and alternative names related to HSD17B4

hydroxysteroid (17-beta) dehydrogenase 4 (hsd17b4), hydroxysteroid 17-beta dehydrogenase 4 (HSD17B4), peroxisomal Multifunctional enzyme type 2 (Mfe2), hydroxysteroid (17-beta) dehydrogenase 4 (Hsd17b4), hydroxysteroid 17-beta dehydrogenase 4 (Hsd17b4), 4, 17-beta-HSD, 17[b]-HSD, CG3415, DBP, Dmel\\CG3415, DmMFE-2, MFE-2, Mfp-2, MFP2, MPF-2, perMFE-2, PRLTS1, SDR8C1, zgc:55545, zgc:77300

Protein level used designations for HSD17B4

  • peroxisomal multifunctional enzyme type 2
  • CG3415-PA
  • Mfe2-PA
  • 17-beta-HSD 4
  • 17-beta-HSD IV
  • 17-beta-hydroxysteroid dehydrogenase 4
  • 17beta-estradiol dehydrogenase type IV
  • 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase
  • D-3-hydroxyacyl-CoA dehydratase
  • D-bifunctional protein, peroxisomal
  • beta-hydroxyacyl dehydrogenase
  • beta-keto-reductase
  • multifunctional protein 2
  • peroxisomal multifunctional protein 2
  • short chain dehydrogenase/reductase family 8C, member 1
  • D-bifunctional protein
  • DBP
  • MFE-2
  • peroxisomal multifunctional enzyme type II
  • 17-beta-hydroxysteroid dehydrogenase type IV
  • 17beta-estradiol dehydrogenase
  • mutifunctional protein2
You are here:
Support