Aldo-Keto Reductase Family 1, Member B10 (Aldose Reductase) (AKR1B10) (AA 76-143), (partial) antibody

Details for Product No. ABIN566074, Supplier: Log in to see
Antigen
  • AKR1B11
  • AKR1B12
  • ALDRLn
  • ARL-1
  • ARL1
  • HIS
  • HSI
  • 2310005E10Rik
  • Akr1b16
  • AKR1B10
  • Akr1b10
  • aldo-keto reductase family 1 member B10
  • aldo-keto reductase family 1, member B10 (aldose reductase)
  • AKR1B10
  • Akr1b10
  • LOC100585902
  • LOC100723118
  • LOC101107697
Epitope
AA 76-143, partial
13
8
8
8
8
7
7
7
5
3
2
2
1
1
1
1
1
Reactivity
Human
81
19
16
2
2
1
1
1
1
1
1
Host
Mouse
51
17
13
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
3
3
3
3
2
2
Application
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)
80
42
18
15
13
4
1
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Immunogen AKR1B10 (NP_064695, 76 a.a. ~ 143 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen sequence: VSKLWPTFFE RPLVRKAFEK TLKDLKLSYL DVYLIHWPQG FKSGDDLFPK DDKGNAIGGK ATFLDAWE
Clone 1A6
Isotype IgG2a kappa
Cross-Reactivity Human
Alternative Name AKR1B10 (AKR1B10 Antibody Abstract)
Background Full Gene Name: aldo-keto reductase family 1, member B10 (aldose reductase)
Synonyms: AKR1B11,AKR1B12,ALDRLn,ARL-1,ARL1,HIS,HSI,MGC14103
Gene ID 57016
NCBI Accession NP_064695, NM_020299
Application Notes Optimal working dilution should be determined by the investigator.
Comment

Product Quality tested by: Antibody Reactive Against Recombinant Protein.

Restrictions For Research Use only
Buffer In 1x PBS, pH 7.4
Handling Advice Aliquot to avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store at -20 °C or lower. Aliquot to avoid repeated freezing and thawing.
Supplier Images
Immunostaining (ISt) image for anti-Aldo-Keto Reductase Family 1, Member B10 (Aldose Reductase) (AKR1B10) (AA 76-143), (partial) antibody (ABIN566074) Immunoperoxidase of monoclonal antibody to AKR1B10 on formalin-fixed paraffin-embedde...
Immunofluorescence (IF) image for anti-Aldo-Keto Reductase Family 1, Member B10 (Aldose Reductase) (AKR1B10) (AA 76-143), (partial) antibody (ABIN566074) Immunofluorescence of monoclonal antibody to AKR1B10 on HeLa cell. [antibody concentr...
Western Blotting (WB) image for anti-Aldo-Keto Reductase Family 1, Member B10 (Aldose Reductase) (AKR1B10) (AA 76-143), (partial) antibody (ABIN566074) AKR1B10 monoclonal antibody (M01), clone 1A6 Western Blot analysis of AKR1B10 express...
ELISA image for anti-Aldo-Keto Reductase Family 1, Member B10 (Aldose Reductase) (AKR1B10) (AA 76-143), (partial) antibody (ABIN566074) Detection limit for recombinant GST tagged AKR1B10 is approximately 0.03ng/ml as a ca...
Western Blotting (WB) image for anti-Aldo-Keto Reductase Family 1, Member B10 (Aldose Reductase) (AKR1B10) (AA 76-143), (partial) antibody (ABIN566074) Western Blot analysis of AKR1B10 expression in transfected 293T cell line by AKR1B10 ...
 image for anti-Aldo-Keto Reductase Family 1, Member B10 (Aldose Reductase) (AKR1B10) (AA 76-143), (partial) antibody (ABIN566074) Western Blot detection against Immunogen (33.22 KDa) .
Immunofluorescence (IF) image for anti-Aldo-Keto Reductase Family 1, Member B10 (Aldose Reductase) (AKR1B10) (AA 76-143), (partial) antibody (ABIN566074) Immunofluorescence of monoclonal antibody to AKR1B10 on HeLa cell. (antibody concentr...
Product cited in: Berard, Coombs, Severini: "Quantification of the host response proteome after herpes simplex virus type 1 infection." in: Journal of proteome research, Vol. 14, Issue 5, pp. 2121-42, 2015 (PubMed).

Matkowskyj, Bai, Liao, Zhang, Li, Rao, Omary, Yang: "Aldoketoreductase family 1B10 (AKR1B10) as a biomarker to distinguish hepatocellular carcinoma from benign liver lesions." in: Human pathology, Vol. 45, Issue 4, pp. 834-43, 2014 (PubMed).

Chung, Matkowskyj, Li, Bai, Zhang, Tsao, Liao, Yang: "Overexpression and oncogenic function of aldo-keto reductase family 1B10 (AKR1B10) in pancreatic carcinoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 25, Issue 5, pp. 758-66, 2012 (PubMed).

Moriguchi, Zhang, Mihara, Sato: "A therapeutic method for the direct reprogramming of human liver cancer cells with only chemicals." in: Scientific reports, Vol. 2, pp. 280, 2012 (PubMed).

Nelson, Pillay, Henderson, Presneau, Tirabosco, Halai, Berisha, Flicek, Stemple, Stern, Wardle, Flanagan: "An integrated functional genomics approach identifies the regulatory network directed by brachyury (T) in chordoma." in: The Journal of pathology, Vol. 228, Issue 3, pp. 274-85, 2012 (PubMed).

Schmitz, Sotiropoulos, Baba, Schmid, Müller, Paul, Auer, Gamerith, Loeffler-Ragg: "AKR1B10 expression is associated with less aggressive hepatocellular carcinoma: a clinicopathological study of 168 cases." in: Liver international : official journal of the International Association for the Study of the Liver, Vol. 31, Issue 6, pp. 810-6, 2011 (PubMed).

Bains, Grigliatti, Reid, Riggs: "Naturally occurring variants of human aldo-keto reductases with reduced in vitro metabolism of daunorubicin and doxorubicin." in: The Journal of pharmacology and experimental therapeutics, Vol. 335, Issue 3, pp. 533-45, 2010 (PubMed).

Satow, Shitashige, Kanai, Takeshita, Ojima, Jigami, Honda, Kosuge, Ochiya, Hirohashi, Yamada: "Combined functional genome survey of therapeutic targets for hepatocellular carcinoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 16, Issue 9, pp. 2518-28, 2010 (PubMed).

Did you look for something else?