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RICTOR antibody (AA 1-98)

RICTOR Reactivity: Human WB, ELISA, IHC (p), IP Host: Mouse Monoclonal 1F3 unconjugated
Catalog No. ABIN566975
  • Target See all RICTOR Antibodies
    RICTOR (RPTOR Independent Companion of mTOR, Complex 2 (RICTOR))
    Binding Specificity
    • 10
    • 9
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-98
    Reactivity
    • 57
    • 32
    • 3
    • 2
    • 1
    Human
    Host
    • 52
    • 5
    • 1
    Mouse
    Clonality
    • 52
    • 6
    Monoclonal
    Conjugate
    • 37
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RICTOR antibody is un-conjugated
    Application
    • 43
    • 32
    • 20
    • 9
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
    Purpose
    Mouse monoclonal antibody raised against a partial recombinant RICTOR.
    Sequence
    MAAIGRGRSL KNLRVRGRND SGEENVPLDL TREPSDNLRE ILQNVARLQG VSNMRKLGHL NNFTKLLCDI GHSEEKLGFH YEDIIICLRL ALLNEAKE
    Cross-Reactivity
    Human
    Characteristics
    Antibody Reactive Against Recombinant Protein.
    Immunogen
    RICTOR (NP_689969, 1 a.a. ~ 98 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    1F3
    Isotype
    IgG2b
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Wu, Schneider, Platen, Mitra, Blazek, Zengerle, Schüle, Meier: "In situ characterization of the mTORC1 during adipogenesis of human adult stem cells on chip." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 29, pp. E4143-50, (2016) (PubMed).

    Pópulo, Tavares, Faustino, Nunes, Lopes, Soares: "GNAQ and BRAF mutations show differential activation of the mTOR pathway in human transformed cells." in: PeerJ, Vol. 1, pp. e104, (2013) (PubMed).

    Faustino, Couto, Pópulo, Rocha, Pardal, Cameselle-Teijeiro, Lopes, Sobrinho-Simões, Soares: "mTOR pathway overactivation in BRAF mutated papillary thyroid carcinoma." in: The Journal of clinical endocrinology and metabolism, Vol. 97, Issue 7, pp. E1139-49, (2012) (PubMed).

    Naïmi, Gautier, Chaussade, Valverde, Accili, Van Obberghen: "Nuclear forkhead box O1 controls and integrates key signaling pathways in hepatocytes." in: Endocrinology, Vol. 148, Issue 5, pp. 2424-34, (2007) (PubMed).

  • Target
    RICTOR (RPTOR Independent Companion of mTOR, Complex 2 (RICTOR))
    Alternative Name
    RICTOR (RICTOR Products)
    Synonyms
    PIA antibody, mAVO3 antibody, 4921505C17Rik antibody, 6030405M08Rik antibody, AVO3 antibody, AW492497 antibody, D530039E11Rik antibody, Fyb antibody, RPTOR independent companion of MTOR complex 2 antibody, RPTOR independent companion of MTOR, complex 2 antibody, RICTOR antibody, Rictor antibody
    Background
    Full Gene Name: rapamycin-insensitive companion of mTOR
    Synonyms: DKFZp686B11164,KIAA1999,MGC39830,mAVO3
    Gene ID
    253260
    NCBI Accession
    NM_152756
    Pathways
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, CXCR4-mediated Signaling Events
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