ACVR2A antibody (C-Term)

Catalog No. ABIN5671355

Product Details anti-ACVR2A Antibody

Target: ACVR2A (Activin A Receptor, Type IIA (ACVR2A))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACVR2A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AYLHEDIPGL KDGHKPAISH RDIKSKNVLL KNNLTACIAD FGLALKFEAG

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against AVR2A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human AVR2A

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ACVR2A

Target: ACVR2A (Activin A Receptor, Type IIA (ACVR2A))

Alternative Name: AVR2A (ACVR2A Products)

Synonyms: ACVR2 antibody, ACVR2A antibody, XSTK9 antibody, actrii antibody, acvr2 antibody, ACTRII antibody, Acvr2 antibody, rActR-II antibody, actr2a antibody, acvr2a antibody, wu:fa02e10 antibody, ActrIIa antibody, TactrII antibody, activin A receptor type 2A antibody, activin A receptor type 2A L homeolog antibody, activin A receptor type 2Aa antibody, activin receptor IIA antibody, ACVR2A antibody, acvr2a antibody, Acvr2a antibody, acvr2a.L antibody, acvr2aa antibody

Background: This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene.

Alias Symbols: ACVR2A, ACVR2,

Protein Interaction Partner: BMP10, GDF2, ACVR1, INHBA, PEG10, ERBB2IP, UBC, IGSF1, MAGI2, TCTEX1D4, SYNJ2BP, GDF9, ACVRL1, INHBC, GDF5, TGFBR3, INHBB, ENG, BMP7, BMP6, ACVR1B, INHA,

Protein Size: 513

Gene ID: 92

NCBI Accession: NP_001607

UniProt: P27037