Mre11 antibody (AA 182-582)

Catalog No. ABIN342349

Product Details anti-Mre11 Antibody

Target: Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

Binding Specificity: AA 182-582

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Mre11 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Specificity: Recognizes human Mre11, an 80 kD protein that acts as a Mn+2- dependent double stranded DNA 3' to 5' exonuclease and a single stranded DNA endonuclease. It is part of a larger complex with Rad50, p95 (Nibrin), and possibly other proteins involved in the nucleolytic end-processing of double strand breaks and telomere maintenance.

Purification: Protein G purified

Immunogen: GST fusion protein corresponding to aa 182-582 of Mre11 expressed in E. coli.

Type of Immunogen: Fusion protein

Isotype: IgG1

Application Details

Application Notes: Approved: IP (1 - 5 μg/mL), WB

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4

Handling Advice: Avoid freeze/thaw cycles.

Storage: -80 °C

Storage Comment: Store at -70°C, avoid freeze/thaw cycles.

Target Details for Mre11

Target: Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

Alternative Name: MRE11A / MRE11 (MRE11A Products)

Synonyms: wu:faa63d12 antibody, zgc:64018 antibody, Mre11 antibody, Mre11b antibody, ATLD antibody, HNGS1 antibody, MRE11 antibody, MRE11B antibody, MRE11 homolog A, double strand break repair nuclease antibody, MRE11 homolog, double strand break repair nuclease antibody, MRE11A homolog A, double strand break repair nuclease antibody, mre11a antibody, MRE11 antibody, Mre11a antibody

Background: Name/Gene ID: MRE11A

Synonyms: MRE11A, AT-like disease, Endo/exonuclease Mre11, HNGS1, MRE11, MRE11 homolog 1, MRE11 homolog A, MRE11B, ATLD

Gene ID: 4361

UniProt: P49959

Pathways: DNA Damage Repair