RAD51 antibody (AA 1-338)

Catalog No. ABIN342351

Product Details anti-RAD51 Antibody

Target: RAD51 (DNA Repair Protein Homolog 1 (RAD51))

Binding Specificity: AA 1-338

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RAD51 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Specificity: Recognizes human Rad51, a 37 kD protein that interacts with BRCA1. This interaction is important for tumor suppression. BRCA2 and Rad51 have also been shown to interact via the BRC repeats located with exon 11 of BRCA2. When these repeats are deleted, the interaction is lost, and cells become hypersensitive to DNA damage caused by methyl methanesulfonate (MMS).

Purification: Protein G purified

Immunogen: GST fusion protein corresponding to full-length Rad51 (aa 1-338) of human Rad51 expressed in E. coli.

Type of Immunogen: Fusion protein

Isotype: IgG2b

Application Details

Application Notes: Approved: IP (1 - 5 μg/mL), WB

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4

Handling Advice: Avoid freeze/thaw cycles.

Storage: -80 °C

Storage Comment: Store at -70°C, avoid freeze/thaw cycles.

Target Details for RAD51

Target: RAD51 (DNA Repair Protein Homolog 1 (RAD51))

Alternative Name: RAD51 / RECA (RAD51 Products)

Synonyms: BRCC5 antibody, HRAD51 antibody, HsRad51 antibody, HsT16930 antibody, MRMV2 antibody, RAD51A antibody, RECA antibody, CRAD51 antibody, wu:fb38e12 antibody, zgc:77754 antibody, RGD1563603 antibody, ATRAD51 antibody, F22D1.20 antibody, F22D1_20 antibody, RAS associated with diabetes protein 51 antibody, AV304093 antibody, Rad51a antibody, Reca antibody, brcc5 antibody, rad51 antibody, rad51a antibody, reca antibody, xrad51 antibody, RAD51 recombinase antibody, RAS associated with diabetes protein 51 antibody, RAD51 recombinase L homeolog antibody, RAD51 antibody, rad51 antibody, Rad51 antibody, rad51.L antibody

Background: Name/Gene ID: RAD51

Synonyms: RAD51, BRCC5, HsT16930, RAD51 homolog A, RAD51 homolog (S. cerevisiae), RecA, E. coli, homolog of, RecA-like protein, Recombination protein A, MRMV2, HRAD51, HsRad51, RAD51A, RECA

Gene ID: 5888

UniProt: Q06609

Pathways: DNA Damage Repair