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DcR2 antibody
TNFRSF10D
Reactivity: Human
IHC, FACS, ICC, IP
Host: Mouse
Monoclonal
HS402
unconjugated
Product Details anti-DcR2 Antibody
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Target
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DcR2 (TNFRSF10D)
(Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D))
Reactivity
All reactivities for DcR2 antibodies
Human
Host
All hosts for DcR2 antibodies
Mouse
Clonality
All clonalities for DcR2 antibodies
Monoclonal
Conjugate
All conjugates for DcR2 antibodies
This DcR2 antibody is un-conjugated
Application
All applications for DcR2 antibodies
Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunoprecipitation (IP)
Specificity
Recognizes human TRAIL-R4. Does not cross-react with human TRAIL-R1, -R2 or -R3.
Purity
> 95% (SDS-PAGE)
Immunogen
Recombinant human TRAIL-R4 (DcR2).
Clone
HS402
Isotype
IgG1
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. In PBS containing 10 % glycerol and 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Stable for at least 1 year after receipt when stored at -20°C.
Target Details for DcR2
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Target
DcR2 (TNFRSF10D)
(Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D))
Alternative Name
TRAIL-R4 (TNFRSF10D Products )
Synonyms
TNFRSF10D antibody, CD264 antibody, DCR2 antibody, TRAIL-R4 antibody, TRAILR4 antibody, TRUNDD antibody, TNF receptor superfamily member 10d antibody, tumor necrosis factor receptor superfamily member 10D antibody, TNFRSF10D antibody, LOC716901 antibody
Background
TRAIL-R4 is a receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis. Protects cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.
Gene ID
8793
UniProt
Q9UBN6
Pathways
Apoptosis
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