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FGF23 antibody

FGF23 Reactivity: Human WB, ELISA, IHC Host: Mouse Monoclonal FG322-3 unconjugated
Catalog No. ABIN5688794
  • Target See all FGF23 Antibodies
    FGF23 (Fibroblast Growth Factor 23 (FGF23))
    Reactivity
    • 58
    • 19
    • 14
    Human
    Host
    • 53
    • 23
    • 2
    Mouse
    Clonality
    • 57
    • 21
    Monoclonal
    Conjugate
    • 41
    • 11
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FGF23 antibody is un-conjugated
    Application
    • 42
    • 33
    • 17
    • 11
    • 9
    • 8
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Specificity
    Recognizes human FGF-23. Does not cross-react with mouse FGF-23.
    Immunogen
    Recombinant human FGF-23.
    Clone
    FG322-3
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product FGF23 Primary Antibody
  • Application Notes
    ELISA: (direct and indirect: 1:2,000-1:5,000). Immunohistochemistry: (paraffin sections (1:100-1:500)). Western Blot: (1:2,000-1:5,000 using ECL. Suggested blocking and dilution buffer is PBST containing 0.05 % Tween 20 and 5 % skim milk. Suggested incubation time is 1 hour at room temperature). Optimal conditions must be determined individually for each application.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid. 0.2um-filtered solution in PBS,  pH 7.4. Contains no preservatives.
    Preservative
    Without preservative
    Storage
    -20 °C
    Storage Comment
    Stable for at least 1 year after receipt when stored at -20°C.
  • Target
    FGF23 (Fibroblast Growth Factor 23 (FGF23))
    Alternative Name
    FGF-23 (FGF23 Products)
    Synonyms
    FGF23 antibody, ADHR antibody, FGFN antibody, HPDR2 antibody, HYPF antibody, PHPTC antibody, fibroblast growth factor 23 antibody, fgf23 antibody, FGF23 antibody, Fgf23 antibody
    Background
    FGF-23 is a regulator of phosphate homeostasis. It upregulates EGR1 expression in the presence of KLBy. Acts directly on the parathyroid to decrease PTH secretion. Regulates the vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization. Defects in FGF-23 are the cause of autosomal dominant hypophosphataemic rickets (ADHR) and of hyperphosphatemic familial tumoral calcinosis (HFTC).
    Gene ID
    8074
    NCBI Accession
    NP_065689
    UniProt
    Q9GZV9
    Pathways
    RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion
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