SLC6A3 antibody (C-Term)

Catalog No. ABIN5688858

Product Details anti-SLC6A3 Antibody

Target: SLC6A3 (Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3 (SLC6A3))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC6A3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Affinity Purified

Immunogen: Peptide from the intracellular C-terminus region of human dopamine transporter (DAT), conjugated to keyhole limpet hemocyanin (KLH).

Application Details

Application Notes: The antibody has been tested in Western blots of SDS-solubilized human and mouse striatal samples and in IHC applications with monkey (Macaque) brain sections.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

Storage: -20 °C

Storage Comment: Dopamine Transporter antibody can be stored at -20°C and is stable at -20°C for at least 1 year.

Target Details for SLC6A3

Target: SLC6A3 (Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3 (SLC6A3))

Alternative Name: Dopamine Transporter (SLC6A3 Products)

Synonyms: DAT antibody, SLC6A3 antibody, Dat1 antibody, DAT1 antibody, PKDYS antibody, solute carrier family 6 member 3 antibody, solute carrier family 6 (neurotransmitter transporter), member 3 antibody, Sodium-dependent dopamine transporter antibody, solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 antibody, SLC6A3 antibody, slc6a3 antibody, dat-1 antibody, Slc6a3 antibody

Background: The dopamine transporter (DAT) is responsible for the reaccumulation of dopamine after it has been released. DAT antibodies and antibodies for other markers of catecholamine biosynthesis are widely used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse (Kish et al., 2001, Zhu et al., 2000, Zhu et al., 1999). Levels of DAT protein expression are altered by chronic drug administration (Wilson et al., 1996).

Molecular Weight: 88 kDa

Gene ID: 6531

UniProt: Q01959

Pathways: Dopaminergic Neurogenesis