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Phospholipase C gamma 2 antibody (AA 751-755)
PLCG2
Reactivity: Human, Rat, Mouse
WB, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Phospholipase C gamma 2 Antibody
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Target
See all Phospholipase C gamma 2 (PLCG2) Antibodies
Phospholipase C gamma 2 (PLCG2)
Binding Specificity
All epitopes for Phospholipase C gamma 2 antibodies
AA 751-755
Reactivity
All reactivities for Phospholipase C gamma 2 antibodies
Human, Rat, Mouse
Host
All hosts for Phospholipase C gamma 2 antibodies
Rabbit
Clonality
All clonalities for Phospholipase C gamma 2 antibodies
Polyclonal
Conjugate
All conjugates for Phospholipase C gamma 2 antibodies
This Phospholipase C gamma 2 antibody is un-conjugated
Application
All applications for Phospholipase C gamma 2 antibodies
Western Blotting (WB), Immunofluorescence (IF)
Specificity
This antibody detects endogenous level of total PLCγ,2 protein.
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Immunogen
PLCgamma2 (Ab-753) antibody was raised against a peptide sequence around aa. 751~755 (S-L-Y-D-V) derived from Human PLCγ,2.
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Alternatives
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Application Details
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Application Notes
Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store antibody at -20°C for up to one year.
Target Details for Phospholipase C gamma 2
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Target
Phospholipase C gamma 2 (PLCG2)
Alternative Name
PLCgamma2 (PLCG2 Products )
Synonyms
PLCgamma2 antibody, Plcg-2 antibody, APLAID antibody, FCAS3 antibody, phospholipase C, gamma 2 antibody, phospholipase C gamma 2 antibody, phospholipase C, gamma 2 (phosphatidylinositol-specific) antibody, Plcg2 antibody, PLCG2 antibody
Background
The production of the second messenger molecules diacylglycerol. (DAG) and inositol 1, 4, 5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.
Molecular Weight
150 kDa
Gene ID
5336
NCBI Accession
NP_002652
UniProt
P16885
Pathways
RTK Signaling , WNT Signaling , Fc-epsilon Receptor Signaling Pathway , Inositol Metabolic Process , Myometrial Relaxation and Contraction , Toll-Like Receptors Cascades , VEGF Signaling , BCR Signaling
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