FOXO3 antibody (AA 251-255)
Quick Overview for FOXO3 antibody (AA 251-255) (ABIN5689400)
Target
See all FOXO3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 251-255
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Specificity
- This antibody detects endogenous level of total FKHRL1 protein.
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Purification
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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Immunogen
- FKHRL1 (Ab-253) antibody was raised against a peptide sequence around aa.251~255 (A-V-S-M-D) derived from Human FKHRL1.
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Application Notes
- Western Blot: 1:500~1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store antibody at -20°C for up to one year.
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- FOXO3 (Forkhead Box O3 (FOXO3))
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Alternative Name
- FKHRL1
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Background
- Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'.
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Molecular Weight
- 97 kDa
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Gene ID
- 2309
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NCBI Accession
- NP_001446
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UniProt
- O43524
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Pathways
- Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis
Target
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