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ASK1 antibody (AA 964-968)
MAP3K5
Reactivity: Human, Mouse, Rat
WB, IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-ASK1 Antibody
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Target
See all ASK1 (MAP3K5) Antibodies
ASK1 (MAP3K5)
(Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5))
Binding Specificity
All epitopes for ASK1 antibodies
AA 964-968
Reactivity
All reactivities for ASK1 antibodies
Human, Mouse, Rat
Host
All hosts for ASK1 antibodies
Rabbit
Clonality
All clonalities for ASK1 antibodies
Polyclonal
Conjugate
All conjugates for ASK1 antibodies
This ASK1 antibody is un-conjugated
Application
All applications for ASK1 antibodies
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Specificity
This antibody detects endogenous level of total ASK1 protein.
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Immunogen
ASK1 (Ab-966) antibody was raised against a peptide sequence around aa.964~968 (S-I-S-L-P) derived from Human ASK1.
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Alternatives
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Application Details
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Application Notes
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store antibody at -20°C for up to one year.
Target Details for ASK1
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Target
ASK1 (MAP3K5)
(Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5))
Alternative Name
ASK1 (MAP3K5 Products )
Synonyms
ASK1 antibody, MAPKKK5 antibody, MEKK5 antibody, mitogen-activated protein kinase kinase kinase 5 antibody, MUD21.11 antibody, MUD21_11 antibody, 7420452D20Rik antibody, ASK antibody, Mekk5 antibody, Ask1 antibody, RGD1306565 antibody, mitogen-activated protein kinase kinase kinase 5 antibody, MAP3K5 antibody, MAPKKK5 antibody, Map3k5 antibody, map3k5 antibody
Background
Component of a protein kinase signal transduction cascade. Phosphorylates and activates MAP2K4 and MAP2K6, which in turn activate the JNK and p38 MAP kinases, respectively. Overexpression induces apoptotic cell death.
Molecular Weight
155 kDa
Gene ID
4217
NCBI Accession
NP_005914
UniProt
Q99683
Pathways
MAPK Signaling , Positive Regulation of Endopeptidase Activity , Unfolded Protein Response
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