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DOK1 antibody (AA 396-400)
DOK1
Reactivity: Human, Mouse, Rat
WB, IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-DOK1 Antibody
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Target
See all DOK1 Antibodies
DOK1
(Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1))
Binding Specificity
All epitopes for DOK1 antibodies
AA 396-400
Reactivity
All reactivities for DOK1 antibodies
Human, Mouse, Rat
Host
All hosts for DOK1 antibodies
Rabbit
Clonality
All clonalities for DOK1 antibodies
Polyclonal
Conjugate
All conjugates for DOK1 antibodies
This DOK1 antibody is un-conjugated
Application
All applications for DOK1 antibodies
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Specificity
This antibody detects endogenous level of total p62Dok protein.
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Immunogen
p62Dok (Ab-398) antibody was raised against a peptide sequence around aa.396~400 (P-I-Y-D-E) derived from Human p62Dok.
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Alternatives
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Application Details
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Application Notes
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store antibody at -20°C for up to one year.
Target Details for DOK1
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Target
DOK1
(Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1))
Alternative Name
p62Dok (DOK1 Products )
Synonyms
P62DOK antibody, Dok-1 antibody, AW557123 antibody, p62DOK antibody, dok1 antibody, zgc:76914 antibody, docking protein 1 antibody, docking protein 1b antibody, DOK1 antibody, Dok1 antibody, dok1b antibody
Background
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.
Molecular Weight
62 kDa
Gene ID
1796
NCBI Accession
NP_001372
UniProt
Q99704
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