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BIM antibody (AA 67-71)
BCL2L11
Reactivity: Human, Mouse, Rat
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-BIM Antibody
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Target
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BIM (BCL2L11)
(BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
Binding Specificity
All epitopes for BIM antibodies
AA 67-71
Reactivity
All reactivities for BIM antibodies
Human, Mouse, Rat
Host
All hosts for BIM antibodies
Rabbit
Clonality
All clonalities for BIM antibodies
Polyclonal
Conjugate
All conjugates for BIM antibodies
This BIM antibody is un-conjugated
Application
All applications for BIM antibodies
Western Blotting (WB), Immunohistochemistry (IHC)
Specificity
This antibody detects endogenous level of total BIM protein.
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Immunogen
BIM (Ab-69) antibody was raised against a peptide sequence around aa.67~71 (P-A-S-P-G) derived from Human BIM.
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Alternatives
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Application Details
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Application Notes
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store antibody at -20°C for up to one year.
Target Details for BIM
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Target
BIM (BCL2L11)
(BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
Alternative Name
BIM (BCL2L11 Products )
Synonyms
bim antibody, BAM antibody, BIM antibody, BOD antibody, 1500006F24Rik antibody, Bim antibody, Bod antibody, BimL antibody, BIMEL antibody, BCL2-like 11 antibody, BCL2 like 11 antibody, BCL2-like 11 (apoptosis facilitator) antibody, bcl2l11 antibody, BCL2L11 antibody, Bcl2l11 antibody
Background
Induces apoptosis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than the isoforms BimEL, BimL and BimS. Isoform Bim-gamma induces apoptosis.
Molecular Weight
23 kDa
Gene ID
10018
NCBI Accession
NP_006529
UniProt
O43521
Pathways
PI3K-Akt Signaling , Neurotrophin Signaling Pathway , Tube Formation , Positive Regulation of Endopeptidase Activity
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