GSK3 alpha antibody (AA 19-23)

Catalog No. ABIN5689508

The Rabbit Polyclonal anti-GSK3 alpha antibody (ABIN5689508) specifically detects GSK3 alpha in WB, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for GSK3 alpha antibody (AA 19-23) (ABIN5689508)

Target: GSK3 alpha (GSK3a) (Glycogen Synthase Kinase 3 alpha (GSK3a))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSK3 alpha antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-GSK3 alpha Antibody

Binding Specificity: AA 19-23

Specificity: This antibody detects endogenous level of total GSK3α, protein. and does not detect GSK-3β, protein.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: GSK3a (Ab-21) antibody was raised against a peptide sequence around aa.19~23 (T-S-S-F-A) derived from Human GSK3α,.

Application Details

Application Notes: Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store antibody at -20°C for up to one year.

Target Details for GSK3 alpha

Target: GSK3 alpha (GSK3a) (Glycogen Synthase Kinase 3 alpha (GSK3a))

Alternative Name: GSK3a

Background: Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN

Molecular Weight: 51 kDa

Gene ID: 2931

NCBI Accession: NP_063937

UniProt: P49840

Pathways: PI3K-Akt Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, BCR Signaling, Warburg Effect