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ENOS antibody (AA 1175-1179)
NOS3
Reactivity: Human, Rat, Mouse
WB, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-ENOS Antibody
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Target
See all ENOS (NOS3) Antibodies
ENOS (NOS3)
(Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))
Binding Specificity
All epitopes for ENOS antibodies
AA 1175-1179
Reactivity
All reactivities for ENOS antibodies
Human, Rat, Mouse
Host
All hosts for ENOS antibodies
Rabbit
Clonality
All clonalities for ENOS antibodies
Polyclonal
Conjugate
All conjugates for ENOS antibodies
This ENOS antibody is un-conjugated
Application
All applications for ENOS antibodies
Western Blotting (WB), Immunofluorescence (IF)
Specificity
This antibody detects endogenous level of total eNOS protein.
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Immunogen
eNOS (Ab-1177) antibody was raised against a peptide sequence around aa.1175~1179 (T-Q-S-F-S) derived from Human eNOS.
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Alternatives
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Application Details
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Application Notes
Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store antibody at -20°C for up to one year.
Target Details for ENOS
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Target
ENOS (NOS3)
(Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))
Alternative Name
eNOS (NOS3 Products )
Synonyms
ECNOS antibody, eNOS antibody, 2310065A03Rik antibody, Nos-3 antibody, ecNOS antibody, EC-NOS antibody, NOSIII antibody, cNOS antibody, NOS antibody, NOS3 antibody, eNos antibody, ENOS antibody, nitric oxide synthase 3 antibody, nitric oxide synthase 3, endothelial cell antibody, NOS3 antibody, Nos3 antibody, nos3 antibody
Background
Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.
Molecular Weight
140 kDa
Gene ID
4846
NCBI Accession
NP_000594
UniProt
P29474
Pathways
ACE Inhibitor Pathway , Regulation of Systemic Arterial Blood Pressure by Hormones , Cellular Response to Molecule of Bacterial Origin , Myometrial Relaxation and Contraction , Signaling Events mediated by VEGFR1 and VEGFR2 , Thromboxane A2 Receptor Signaling , VEGFR1 Specific Signals , VEGF Signaling
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