VEGFR2/CD309 antibody (AA 1057-1061)

Catalog No. ABIN5689591

The Rabbit Polyclonal anti-VEGFR2/CD309 antibody is suitable to detect VEGFR2/CD309 in samples from Human and Mouse. It has been validated for WB.

Quick Overview for VEGFR2/CD309 antibody (AA 1057-1061) (ABIN5689591)

Target: VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VEGFR2/CD309 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-VEGFR2/CD309 Antibody

Binding Specificity: AA 1057-1061

Specificity: This antibody detects endogenous levels of total VEGFR2 protein.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: VEGFR2 (Ab-1059) antibody was raised against a peptide sequence around aa. 1057~1061 (P-D-Y-V-R) derived from Human VEGFR2.

Application Details

Application Notes: Western Blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store antibody at -20°C for up to one year.

Target Details for VEGFR2/CD309

Target: VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Alternative Name: VEGFR2

Background: Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions

Molecular Weight: 210, 230 kDa

Gene ID: 3791

NCBI Accession: NP_002244

UniProt: P35968

Pathways: RTK Signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling