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RIMS2 antibody (AA 30-80)
RIMS2
Reactivity: Human
ELISA, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-RIMS2 Antibody
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Target
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RIMS2
(Regulating Synaptic Membrane Exocytosis 2 (RIMS2))
Binding Specificity
All epitopes for RIMS2 antibodies
AA 30-80
Reactivity
All reactivities for RIMS2 antibodies
Human
Host
All hosts for RIMS2 antibodies
Rabbit
Clonality
All clonalities for RIMS2 antibodies
Polyclonal
Conjugate
All conjugates for RIMS2 antibodies
This RIMS2 antibody is un-conjugated
Application
All applications for RIMS2 antibodies
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
RIM2 Antibody is affinity chromatography purified via peptide column.
Immunogen
RIM2 antibody was raised against a 16 amino acid peptide near the carboxy terminusof human RIM2. The immunogen is located within amino acids 30 - 80 of RIM2.
Isotype
IgG
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Discover our top product RIMS2 Primary Antibody
Alternatives
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Application Details
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Application Notes
RIM2 antibody can be used for detection of RIM2 by immunohistochemistry at 5 μ,g/mL.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
RIM2 Antibody is supplied in PBS containing 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
RIM2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Target Details for RIMS2
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Target
RIMS2
(Regulating Synaptic Membrane Exocytosis 2 (RIMS2))
Alternative Name
RIM2 (RIMS2 Products )
Synonyms
OBOE antibody, RAB3IP3 antibody, RIM2 antibody, 2810036I15Rik antibody, AW048769 antibody, Rab3ip2 antibody, Rim2(+40A) antibody, Rim2(+44A) antibody, Rim2(+4A) antibody, Serg2 antibody, Syt3-rs antibody, mKIAA0751 antibody, Nim2 antibody, Rim2 antibody, RIMS2 antibody, MGC159469 antibody, rims2 antibody, zgc:73064 antibody, drs antibody, drsp antibody, mema antibody, np-a antibody, pinin antibody, pnn antibody, pnn-a antibody, pnn-b antibody, sdk3 antibody, regulating synaptic membrane exocytosis 2 antibody, regulating synaptic membrane exocytosis 2a antibody, pinin, desmosome associated protein S homeolog antibody, RIMS2 antibody, Rims2 antibody, rims2a antibody, pnn.S antibody
Background
RIM2 Antibody: Rab3-interacting molecules (RIMs) are synaptic proteins necessary for neuronal transmission and plasticity. RIM1 and RIM2 proteins are expressed in overlapping but distinct patterns throughout the brain. While the ablation of either gene was not lethal in mice, the deletion of both resulted in postnatal mortality. This lethality is due to a defect in neurotransmitter release, synapses without RIM proteins can still release neurotransmitters but are unable to do so in response to normal Ca2+ triggers. Like RIM1, RIM2 is thought to be an effector protein for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner.
Molecular Weight
Predicted: 148 kDa
Gene ID
9699
NCBI Accession
NP_001093587
UniProt
Q9UQ26
Pathways
Hormone Transport , Synaptic Vesicle Exocytosis
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