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WAC antibody (AA 210-260)
WAC
Reactivity: Human, Mouse, Rat
ELISA, WB, IF, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-WAC Antibody
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Target
See all WAC Antibodies
WAC
(WW Domain Containing Adaptor with Coiled-Coil (WAC))
Binding Specificity
All epitopes for WAC antibodies
AA 210-260
Reactivity
All reactivities for WAC antibodies
Human, Mouse, Rat
Host
All hosts for WAC antibodies
Rabbit
Clonality
All clonalities for WAC antibodies
Polyclonal
Conjugate
All conjugates for WAC antibodies
This WAC antibody is un-conjugated
Application
All applications for WAC antibodies
ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificity
At least two isoforms of WAC are known to exist, this antibody will detect the larger isoform.
Purification
WAC Antibody is affinity chromatography purified via peptide column.
Immunogen
WAC antibody was raised against a 19 amino acid peptide near the center of human WAC . The immunogen is located within amino acids 210 - 260 of WAC.
Isotype
IgG
Top Product
Discover our top product WAC Primary Antibody
Alternatives
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Application Details
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Application Notes
WAC Antibody can be used for detection of WAC by Western blot at 1 μ,g/mL.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
WAC Antibody is supplied in PBS containing 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
WAC antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Target Details for WAC
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Target
WAC
(WW Domain Containing Adaptor with Coiled-Coil (WAC))
Alternative Name
WAC (WAC Products )
Synonyms
BM-016 antibody, PRO1741 antibody, Wwp4 antibody, 1110067P07Rik antibody, A230035H12Rik antibody, AI256735 antibody, AI256776 antibody, DKFZp468H162 antibody, wac antibody, wu:fc13f04 antibody, wu:fj68f01 antibody, zgc:55755 antibody, RGD1562407 antibody, zgc:101828 antibody, WW domain containing adaptor with coiled-coil antibody, WW domain containing adaptor with coiled-coil a antibody, WW domain containing adaptor with coiled-coil b antibody, WAC antibody, Wac antibody, wac antibody, waca antibody, wacb antibody
Background
WAC Antibody: The WW domain containing adaptor with coiled-coil protein (WAC) contains a WW domain that mediates protein-protein interactions and colocalizes with RNA splicing factor SC35. Further studies have indicated that WAC is a functional partner of the RNF20/40 complex that ubiquitinates Histone H2B, and that WAC regulates H2B ubiquitination. WAC targets RNF20/40 to associate with RNA polymerase II complex for H2B ubiquitination at active transcription sites. WAC-dependent transcription is also important for cell-cycle checkpoint activation in response to genotoxic stress.
Molecular Weight
Predicted: 71 kDa Observed: 75 kDa
Gene ID
51322
NCBI Accession
NP_057712
UniProt
Q9BTA9
Pathways
Chromatin Binding
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