BMF antibody

Catalog No. ABIN5690624

Product Details anti-BMF Antibody

Target: BMF (Bcl2 Modifying Factor (BMF))

Reactivity: Human, Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This BMF antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS)

Specificity: Recognizes human and mouse Bmf. Detects several cross-reactivity bands of unknown identity in mice by western blot.

Purity: > 95% (SDS-PAGE)

Immunogen: Recombinant mouse Bmf.

Clone: 9G10

Isotype: IgG2a kappa

Application Details

Application Notes: Flow Cytometry: (overexpressed in cell lines). Immunoprecipitation: (1-5 μg/mL). Western Blot: (1-2 μg/mL).

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. In PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for at least 1 year after receipt when stored at -20°C.

Target Details for BMF

Target: BMF (Bcl2 Modifying Factor (BMF))

Alternative Name: Bmf (BMF Products)

Synonyms: BMF antibody, AW260063 antibody, AW411872 antibody, Bcl2 modifying factor antibody, Bcl2 modifying factor L homeolog antibody, BCL2 modifying factor antibody, BMF antibody, bmf.L antibody, Bmf antibody

Background: Bmf (Bcl-2-modifying factor) belongs to the Bcl-2 protein family. Bcl-2 family members form hetero- or homo-dimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bmf contains a single Bcl-2 homology domain 3 (BH3), and has been shown to interact with other Bcl-2 proteins and functions as an apoptotic activator. Two different start sites can give rise to two proteins of 25 or 30 kDa. It is found to be sequestered to myosin V motors by its association with dynein light chain 2 (DLC2), which may be important for sensing intracellular damage and triggering apoptosis.

Gene ID: 90427

NCBI Accession: NP_277038

UniProt: Q96LC9