HNRNPK antibody
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- Target See all HNRNPK Antibodies
- HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HNRNPK antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS)
- Immunogen
- heterogeneous nuclear ribonucleoprotein K
- Isotype
- IgG
- Top Product
- Discover our top product HNRNPK Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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HeLa cells were subjected to SDS PAGE followed by western blot with FNab03955(HNRNPK antibody) at dilution of 1:300
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))
- Alternative Name
- HNRNPK (HNRNPK Products)
- Synonyms
- CSBP antibody, HNRPK antibody, TUNP antibody, Csbp antibody, Hnrpk antibody, hnrpk antibody, MGC75642 antibody, wu:fb37h02 antibody, wu:fi34c04 antibody, zgc:66162 antibody, KBBP antibody, NOVA antibody, heterogeneous nuclear ribonucleoprotein K antibody, heterogeneous nuclear ribonucleoprotein K S homeolog antibody, heterogeneous nuclear ribonucleoprotein k antibody, HNRNPK antibody, Hnrnpk antibody, hnrnpk.S antibody, hnrnpk antibody, LOC5565718 antibody, CpipJ_CPIJ000130 antibody, NGK_p0004 antibody
- Background
- Synonyms:CSBP, hnRNP K, HNRNPK, HNRPK, TUNP Background:One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction(By similarity). As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21(lincRNA-p21), a non-coding RNA induced by p53/TP53. This interaction is necessary for the induction of apoptosis, but not cell cycle arrest.
- Molecular Weight
- 51 kDa
- Gene ID
- 3190
- UniProt
- P61978
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