MBD2 antibody
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- Target See all MBD2 Antibodies
- MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
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Reactivity
- Human, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MBD2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Immunogen
- methyl-CpG binding domain protein 2
- Isotype
- IgG
- Top Product
- Discover our top product MBD2 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
- Alternative Name
- MBD2 (MBD2 Products)
- Synonyms
- MBD2 antibody, DMTase antibody, NY-CO-41 antibody, MBD2a antibody, wu:fa97f06 antibody, zgc:111862 antibody, methyl-CpG binding domain protein 2 antibody, methyl-CpG binding domain protein 2 S homeolog antibody, MBD2 antibody, Mbd2 antibody, mbd2 antibody, mbd2.S antibody
- Background
- Synonyms: Background:Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters.
- Molecular Weight
- 43-45 kDa
- Gene ID
- 8932
- UniProt
- Q9UBB5
- Pathways
- Chromatin Binding
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