RIN1 antibody

Catalog No. ABIN5698331

Product Details anti-RIN1 Antibody

Target: RIN1 (Ras and Rab Interactor 1 (RIN1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RIN1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Immunogen: Ras and Rab interactor 1

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for RIN1

Target: RIN1 (Ras and Rab Interactor 1 (RIN1))

Alternative Name: RIN1 (RIN1 Products)

Synonyms: RIN1 antibody, Ras and Rab interactor 1 antibody, RIN1 antibody, Rin1 antibody

Background: Synonyms: Background:Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor(GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.

Gene ID: 9610

UniProt: Q13671