Stim2 antibody
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- Target See all Stim2 Antibodies
- Stim2 (Stromal Interaction Molecule 2 (Stim2))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Stim2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
- Immunogen
- stromal interaction molecule 2
- Isotype
- IgG
- Top Product
- Discover our top product Stim2 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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HeLa cells were subjected to SDS PAGE followed by western blot with FNab08322( STIM2 Antibody) at dilution of 1:1000
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- Stim2 (Stromal Interaction Molecule 2 (Stim2))
- Alternative Name
- STIM2 (Stim2 Products)
- Synonyms
- STIM2 antibody, stromal interaction molecule 2 antibody, STIM2 antibody, stim2 antibody, Stim2 antibody
- Background
- Synonyms:KIAA1482 Background:Plays a role in mediating store-operated Ca(2+) entry(SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Functions as a highly sensitive Ca(2+) sensor in the endoplasmic reticulum which activates both store-operated and store-independent Ca(2+)-influx. Regulates basal cytosolic and endoplasmic reticulum Ca(2+) concentrations. Upon mild variations of the endoplasmic reticulum Ca(2+) concentration, translocates from the endoplasmic reticulum to the plasma membrane where it probably activates the Ca(2+) release-activated Ca(2+)(CRAC) channels ORAI1, ORAI2 and ORAI3. May inhibit STIM1-mediated Ca(2+) influx.
- Gene ID
- 57620
- UniProt
- Q9P246
- Pathways
- TCR Signaling, BCR Signaling
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