TULP3 antibody

Catalog No. ABIN5698652

Product Details anti-TULP3 Antibody

Target: TULP3 (Tubby Like Protein 3 (TULP3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TULP3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogen: tubby like protein 3

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:5000,IHC:1:20-1:200,IP:1:200-1:2000

Comment:

SH-SY5Y cells were subjected to SDS PAGE followed by western blot with FNab09109(TULP3 antibody) at dilution of 1:800

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for TULP3

Target: TULP3 (Tubby Like Protein 3 (TULP3))

Alternative Name: TULP3 (TULP3 Products)

Synonyms: tubl3 antibody, DKFZp469I1734 antibody, TUBL3 antibody, 2310022L06Rik antibody, AI316887 antibody, tubby like protein 3 antibody, tubby-like protein 3 antibody, TULP3 antibody, tulp3 antibody, Tulp3 antibody

Background: Synonyms:Tubby like protein 3, Tubby related protein 3, TUBL3, TULP3 Background:Negative regulator of the Shh signaling transduction pathway: recruited to primary cilia via association with the IFT complex A(IFT-A) and is required for recruitment of G protein-coupled receptor GPR161 to cilia, a promoter of PKA-dependent basal repression machinery in Shh signaling. Binds to phosphorylated inositide(phosphoinositide) lipids. Both IFT-A-and phosphoinositide-binding properties are required to regulate ciliary G protein-coupled receptor trafficking. Not involved in ciliogenesis.

Molecular Weight: 59kDa

Gene ID: 7289

UniProt: O75386

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Tube Formation