PQBP1 antibody
-
- Target See all PQBP1 Antibodies
- PQBP1 (Polyglutamine Binding Protein 1 (PQBP1))
-
Reactivity
- Human, Mouse, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This PQBP1 antibody is un-conjugated
-
Application
- Western Blotting (WB), ELISA
- Immunogen
- polyglutamine binding protein 1
- Isotype
- IgG
- Top Product
- Discover our top product PQBP1 Primary Antibody
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
-
- Target
- PQBP1 (Polyglutamine Binding Protein 1 (PQBP1))
- Alternative Name
- PQBP1 (PQBP1 Products)
- Synonyms
- PQBP1 antibody, MRX55 antibody, MRXS3 antibody, MRXS8 antibody, NPW38 antibody, RENS1 antibody, SHS antibody, PQBP-1 antibody, Sfc2 antibody, npw38 antibody, polyglutamine binding protein 1 antibody, PQBP1 antibody, Pqbp1 antibody
- Background
- Synonyms:NPW38 Background:Probably functions as scaffold protein that is part of numerous complexes and thereby plays a role in pre-mRNA splicing, transcription regulation and neuron development. Required for normal alternative splicing of target pre-mRNA species(PubMed:23512658). May suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner. Can activate transcription directly or via association with the transcription machinery. May be involved in ATXN1 mutant-induced cell death. The interaction with ATXN1 mutant reduces levels of phosphorylated RNA polymerase II large subunit.
- Gene ID
- 10084
- UniProt
- O60828
- Pathways
- Ribonucleoprotein Complex Subunit Organization
-