ARL3 antibody

Catalog No. ABIN5699145

Product Details anti-ARL3 Antibody

Target: ARL3 (ADP-Ribosylation Factor-Like 3 (ARL3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARL3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Immunogen: ADP-ribosylation factor-like 3

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

HeLa cells were subjected to SDS PAGE followed by western blot with FNab00576(ARL3 antibody) at dilution of 1:1000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for ARL3

Target: ARL3 (ADP-Ribosylation Factor-Like 3 (ARL3))

Alternative Name: ARL3 (ARL3 Products)

Synonyms: ARFL3 antibody, si:ch211-208d15.4 antibody, wu:fj22g05 antibody, arfl3 antibody, arl3 antibody, ADP ribosylation factor like GTPase 3 antibody, ADP-ribosylation factor-like 3 antibody, ADP ribosylation factor like GTPase 3 S homeolog antibody, ADP-ribosylation factor-like protein 3 antibody, ARL3 antibody, arl3 antibody, Arl3 antibody, arl3.1.S antibody, arl-3 antibody

Background: Synonyms:ARFL3 Background:Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors(GEF) and GTPase-activating proteins(GAP). Required for normal cytokinesis and cilia signaling. Requires assistance from GTPase-activating proteins(GAPs) like RP2 and PDE6D, in order to cycle between inactive GDP-bound and active GTP-bound forms. Required for targeting proteins such as NPHP3 to the ciliary membrane by releasing myristoylated NPHP3 from UNC119B cargo adapter into the cilium. Does not act as an allosteric activator of the cholera toxin catalytic subunit.

Molecular Weight: 20 kDa

Gene ID: 403

UniProt: P36405