GSDMD antibody

Catalog No. ABIN5699829

Product Details anti-GSDMD Antibody

Target: GSDMD (Gasdermin D (GSDMD))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSDMD antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Immunogen: gasdermin D

Isotype: IgG

Application Details

Application Notes: WB : 1:200-1:2000 IHC : 1:20-1:200 IF : 1:10-1:100

Comment:

Jurkat cells were subjected to SDS PAGE followed by western blot with FNab03670( GSDMD Antibody) at dilution of 1:500

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for GSDMD

Target: GSDMD (Gasdermin D (GSDMD))

Alternative Name: GSDMD (GSDMD Products)

Synonyms: GSDMDC1 antibody, GSDMD antibody, DF5L antibody, DFNA5L antibody, 1810036L03Rik antibody, AW558049 antibody, Dfna5l antibody, Gsdmdc1 antibody, M2-4 antibody, gasdermin D antibody, GSDMD antibody, Gsdmd antibody

Background: Synonyms:DF5L, DFNA5L, FKSG10, FLJ12150, gasdermin D, GSDMD, GSDMDC1 Background:GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.

Molecular Weight: 50-53 kDa

Gene ID: 79792

UniProt: P57764

Pathways: Inflammasome