METAP2 antibody
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- Target See all METAP2 Antibodies
- METAP2 (Methionyl Aminopeptidase 2 (METAP2))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This METAP2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Immunogen
- methionyl aminopeptidase 2
- Isotype
- IgG
- Top Product
- Discover our top product METAP2 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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HepG2 cells were subjected to SDS PAGE followed by western blot with FNab05135(METAP2 antibody) at dilution of 1:300
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- METAP2 (Methionyl Aminopeptidase 2 (METAP2))
- Alternative Name
- METAP2 (METAP2 Products)
- Synonyms
- metap2 antibody, MGC53792 antibody, METAP2 antibody, GB13458 antibody, DDBDRAFT_0190923 antibody, DDBDRAFT_0304991 antibody, DDB_0190923 antibody, DDB_0304991 antibody, 4930584B20Rik antibody, A930035J23Rik antibody, AI047573 antibody, AL024412 antibody, AU014659 antibody, Amp2 antibody, Mnpep antibody, p67 antibody, p67eIF2 antibody, MAP2 antibody, MNPEP antibody, wu:fb98h06 antibody, zgc:66250 antibody, methionyl aminopeptidase 2 L homeolog antibody, methionyl aminopeptidase 2 antibody, methionine aminopeptidase 2 antibody, methionine aminopeptidase antibody, methionyl aminopeptidase 2 S homeolog antibody, methionyl aminopeptidase 2b antibody, metap2.L antibody, METAP2 antibody, metap2 antibody, LOC551771 antibody, CAALFM_C604080WA antibody, Metap2 antibody, metap2.S antibody, metap2b antibody
- Background
- Synonyms:MNPEP, P67EIF2 Background:Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged(Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). The catalytic activity of human METAP2 toward Met-Val peptides is consistently two orders of magnitude higher than that of METAP1, suggesting that it is responsible for processing proteins containing N-terminal Met-Val and Met-Thr sequences in vivo. Protects eukaryotic initiation factor EIF2S1 from translation-inhibiting phosphorylation by inhibitory kinases such as EIF2AK2/PKR and EIF2AK1/HCR. Plays a critical role in the regulation of protein synthesis.
- Molecular Weight
- 67 kDa
- Gene ID
- 10988
- UniProt
- P50579
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling
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