EZH1 antibody

Catalog No. ABIN5700849

Product Details anti-EZH1 Antibody

Target: EZH1 (Enhancer of Zeste Homolog 1 (EZH1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EZH1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Immunogen: enhancer of zeste homolog 1 (Drosophila)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for EZH1

Target: EZH1 (Enhancer of Zeste Homolog 1 (EZH1))

Alternative Name: EZH1 (EZH1 Products)

Synonyms: KMT6B antibody, si:ch211-250i3.1 antibody, zgc:136829 antibody, AW557915 antibody, mKIAA0388 antibody, EZH1 antibody, enhancer of zeste 1 polycomb repressive complex 2 subunit antibody, EZH1 antibody, ezh1 antibody, Ezh1 antibody

Background: Synonyms:KIAA0388 Background:Polycomb group(PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di-and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH2-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.

Molecular Weight: 77-86 kDa,69 kDa

Gene ID: 2145

UniProt: Q92800