Urm1 antibody
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- Target See all Urm1 Antibodies
- Urm1 (Ubiquitin Related Modifier 1 (Urm1))
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Urm1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Immunogen
- ubiquitin related modifier 1 homolog (S. cerevisiae)
- Isotype
- IgG
- Top Product
- Discover our top product Urm1 Primary Antibody
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- Application Notes
- WB : 1:500-1:5000,IHC:1:20-1:200
- Comment
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human placenta tissue were subjected to SDS PAGE followed by western blot with FNab09289(URM1 antibody) at dilution of 1:1000
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- Urm1 (Ubiquitin Related Modifier 1 (Urm1))
- Alternative Name
- URM1 (Urm1 Products)
- Synonyms
- RGD1306599 antibody, C9orf74 antibody, 2900073H19Rik antibody, ubiquitin related modifier 1 antibody, ubiquitin related modifier antibody, ubiquitin-related modifier antibody, Ubiquitin-related modifier 1 homolog antibody, Urm1 antibody, LOC733109 antibody, URM1 antibody
- Background
- Synonyms:URM1, C9orf74 Background:Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated(-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein(UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as MOCS3, ATPBD3, CTU2, USP15 and CAS. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
- Molecular Weight
- 104kDa
- Gene ID
- 81605
- UniProt
- Q9BTM9
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