USP19 antibody

Catalog No. ABIN5701384

Product Details anti-USP19 Antibody

Target: USP19 (Ubiquitin Specific Peptidase 19 (USP19))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP19 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Immunogen: ubiquitin specific peptidase 19

Isotype: IgG

Application Details

Application Notes: WB : 1:200-1:2000,IP:1:200-1:2000

Comment:

Jurkat cells were subjected to SDS PAGE followed by western blot with FNab09314( USP19 Antibody) at dilution of 1:600

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for USP19

Target: USP19 (Ubiquitin Specific Peptidase 19 (USP19))

Alternative Name: USP19 (USP19 Products)

Synonyms: wu:fc26a05 antibody, si:dkey-32e6.9 antibody, USP19 antibody, MGC145127 antibody, ZMYND9 antibody, 8430421I07Rik antibody, AI047774 antibody, Zmynd9 antibody, ubiquitin specific peptidase 19 antibody, universal stress protein antibody, ubiquitin carboxyl-terminal hydrolase 19 antibody, usp19 antibody, USP19 antibody, RR_RS18085 antibody, PTRG_09611 antibody, Usp19 antibody

Background: Synonyms:Deubiquitinating enzyme 19, KIAA0891, Ubiquitin thiolesterase 19, USP19, ZMYND9 Background:Deubiquitinating enzyme that regulates the degradation of various proteins. Deubiquitinates and prevents proteasomal degradation of RNF123 which in turn stimulates CDKN1B ubiquitin-dependent degradation thereby playing a role in cell proliferation. Involved in decreased protein synthesis in atrophying skeletal muscle. Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic-reticulum-associated degradation(ERAD) substrates. Regulates the stability of BIRC2/c-IAP1 and BIRC3/c-IAP2 by preventing their ubiquitination. Required for cells to mount an appropriate response to hypoxia and rescues HIF1A from degradation in a non-catalytic manner. Plays an important role in 17 beta-estradiol(E2)-inhibited myogenesis. Decreases the levels of ubiquitinated proteins during skeletal muscle formation and acts to repress myogenesis. Exhibits a preference towards 'Lys-63'-linked Ubiquitin chains.

Molecular Weight: 43kDa,Observed 70kDa,43kDa

Gene ID: 10869

UniProt: O94966