WAPAL antibody

Catalog No. ABIN5701429

Product Details anti-WAPAL Antibody

Target: WAPAL (Wings Apart-Like Protein Homolog (WAPAL))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WAPAL antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Immunogen: wings apart-like homolog (Drosophila)

Isotype: IgG

Application Details

Application Notes: WB : 1:500-1:5000

Comment:

HL-60 cells were subjected to SDS PAGE followed by western blot with FNab09467(WAPL, WAPAL antibody) at dilution of 1:300

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for WAPAL

Target: WAPAL (Wings Apart-Like Protein Homolog (WAPAL))

Alternative Name: WAPL, WAPAL (WAPAL Products)

Synonyms: RGD1308960 antibody, FOE antibody, KIAA0261 antibody, WAPL antibody, 2410073G16 antibody, A530089A20Rik antibody, BC037674 antibody, mKIAA0261 antibody, mWAPL antibody, WAPL cohesin release factor antibody, Wapl antibody, WAPL antibody, wapl antibody

Background: Synonyms:FOE, Friend of EBNA2 protein, KIAA0261, WAPAL, WAPL Background:The wings apart-like(WAPL, or WAPAL) protein was originally identified as a gene product that potentially regulates heterochromatin organization in Drosophila melanogaster. Human WAPL is a cohesin-binding protein that promotes sister-chromatid resolution in mitotic prophase. Overexpression of WAPL disturbs mitosis and cytokinesis, and contributes to tumor progression by induction of chromosomal instability.

Molecular Weight: 309kDa,observed 70kDa,309kDa

UniProt: Q7Z5K2

Pathways: Chromatin Binding