MLXIP antibody

Catalog No. ABIN5701831

Product Details anti-MLXIP Antibody

Target: MLXIP (MLX Interacting Protein (MLXIP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MLXIP antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Immunogen: MLX interacting protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

K-562 cells were subjected to SDS PAGE followed by western blot with FNab05223(MLXIP antibody) at dilution of 1:500

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for MLXIP

Target: MLXIP (MLX Interacting Protein (MLXIP))

Alternative Name: MLXIP (MLXIP Products)

Synonyms: MGC83884 antibody, si:ch211-110p13.4 antibody, MIR antibody, MONDOA antibody, bHLHe36 antibody, AW228700 antibody, B930074I24 antibody, Mir antibody, mKIAA0867 antibody, RGD1560774 antibody, MLX interacting protein antibody, MLX interacting protein L homeolog antibody, MLXIP antibody, mlxip.L antibody, mlxip antibody, Mlxip antibody

Background: Synonyms:BHLHE36, KIAA0867, MIR, MONDOA Background:Mlx-interacting protein(MLXIP), after forming heterodimers with MLX, can bind to and then activate transcription from CACGTG E boxes. The N terminus of MLXIP acts as a CRM1-dependent nuclear export signal and contribute to the cytoplasmic localization of the complex, and as a binding site for 13 protein. the C terminus contains a cytoplasmic localization signal and mediates protein-protein interaction of MONDOA and MLX. The complex play a role in transcriptional activation of glycolytic target genes and glucose-responsive gene regulation. This antibody could recognize isoform1(~110kd) and isoform3(~69kd) of MLXIP. A specific MLXIP of approximately 130 kDa was detected. It demonstrates that MLXIP associated specifically with Mlx in the cytoplasm (PMID: 11073985).

Molecular Weight: 130 kDa

Gene ID: 22877

UniProt: Q9HAP2