FBXO22 antibody

Catalog No. ABIN5702274

Product Details anti-FBXO22 Antibody

Target: FBXO22 (F-Box Protein 22 (FBXO22))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO22 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogen: F-box protein 22

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

HeLa cells were subjected to SDS PAGE followed by western blot with FNab03041(FBXO22 antibody) at dilution of 1:500

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for FBXO22

Target: FBXO22 (F-Box Protein 22 (FBXO22))

Alternative Name: FBXO22 (FBXO22 Products)

Synonyms: FBXO22 antibody, DKFZp469L0535 antibody, fbxo22 antibody, MGC146708 antibody, si:busm1-132m23.3 antibody, FBX22 antibody, FISTC1 antibody, 0610033L19Rik antibody, 1600016C16Rik antibody, F-box protein 22 antibody, FBXO22 antibody, fbxo22 antibody, Fbxo22 antibody

Background: Synonyms:FBX22 Background:Substrate-recognition component of the SCF(SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Promotes the proteasome-dependent degradation of key sarcomeric proteins, such as alpha-actinin(ACTN2) and filamin-C(FLNC), essential for maintenance of normal contractile function.

Molecular Weight: 45 kDa

Gene ID: 26263

UniProt: Q8NEZ5

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development