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BUB3 antibody

BUB3 Reactivity: Human, Mouse, Rat ELISA, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5702423
  • Target See all BUB3 Antibodies
    BUB3 (Budding Uninhibited By Benzimidazoles 3 Homolog (Yeast) (BUB3))
    Reactivity
    • 49
    • 36
    • 31
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 63
    • 1
    • 1
    • 1
    Rabbit
    Clonality
    • 56
    • 10
    Polyclonal
    Conjugate
    • 34
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This BUB3 antibody is un-conjugated
    Application
    • 46
    • 18
    • 17
    • 14
    • 14
    • 14
    • 12
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    ELISA, Immunofluorescence (IF)
    Immunogen
    budding uninhibited by benzimidazoles 3 homolog (yeast)
    Isotype
    IgG
    Top Product
    Discover our top product BUB3 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze / thaw cycles.
    Storage
    -20 °C
    Expiry Date
    12 months
  • Target
    BUB3 (Budding Uninhibited By Benzimidazoles 3 Homolog (Yeast) (BUB3))
    Alternative Name
    BUB3 (BUB3 Products)
    Synonyms
    BUB3L antibody, hBUB3 antibody, Aa2-050 antibody, xbub3 antibody, AU019800 antibody, AU021329 antibody, AU043350 antibody, AW146323 antibody, C78067 antibody, BUB3, mitotic checkpoint protein antibody, BUB3 mitotic checkpoint protein antibody, BUB3 mitotic checkpoint protein L homeolog antibody, BUB3 antibody, Bub3 antibody, bub3.L antibody
    Background
    Synonyms: Background:Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule(K-MT) attachments. Promotes the formation of stable end-on bipolar attachments. Necessary for kinetochore localization of BUB1. Regulates chromosome segregation during oocyte meiosis. The BUB1/BUB3 complex plays a role in the inhibition of anaphase-promoting complex or cyclosome(APC/C) when spindle-assembly checkpoint is activated and inhibits the ubiquitin ligase activity of APC/C by phosphorylating its activator CDC20. This complex can also phosphorylate MAD1L1.
    Gene ID
    9184
    UniProt
    O43684
    Pathways
    Maintenance of Protein Location
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