×
For best experience we recommend to activate Javascript in your browser.
BUB3 antibody
BUB3
Reactivity: Human, Mouse, Rat
ELISA, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-BUB3 Antibody
(hide)
Target
See all BUB3 Antibodies
BUB3
(Budding Uninhibited By Benzimidazoles 3 Homolog (Yeast) (BUB3))
Reactivity
All reactivities for BUB3 antibodies
Human, Mouse, Rat
Host
All hosts for BUB3 antibodies
Rabbit
Clonality
All clonalities for BUB3 antibodies
Polyclonal
Conjugate
All conjugates for BUB3 antibodies
This BUB3 antibody is un-conjugated
Application
All applications for BUB3 antibodies
ELISA, Immunofluorescence (IF)
Immunogen
budding uninhibited by benzimidazoles 3 homolog (yeast)
Isotype
IgG
Top Product
Discover our top product BUB3 Primary Antibody
Alternatives
(show)
Application Details
(hide)
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
(hide)
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freeze / thaw cycles.
Storage
-20 °C
Expiry Date
12 months
Target Details for BUB3
(hide)
Target
BUB3
(Budding Uninhibited By Benzimidazoles 3 Homolog (Yeast) (BUB3))
Alternative Name
BUB3 (BUB3 Products )
Synonyms
BUB3L antibody, hBUB3 antibody, Aa2-050 antibody, xbub3 antibody, AU019800 antibody, AU021329 antibody, AU043350 antibody, AW146323 antibody, C78067 antibody, BUB3, mitotic checkpoint protein antibody, BUB3 mitotic checkpoint protein antibody, BUB3 mitotic checkpoint protein L homeolog antibody, BUB3 antibody, Bub3 antibody, bub3.L antibody
Background
Synonyms: Background:Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule(K-MT) attachments. Promotes the formation of stable end-on bipolar attachments. Necessary for kinetochore localization of BUB1. Regulates chromosome segregation during oocyte meiosis. The BUB1/BUB3 complex plays a role in the inhibition of anaphase-promoting complex or cyclosome(APC/C) when spindle-assembly checkpoint is activated and inhibits the ubiquitin ligase activity of APC/C by phosphorylating its activator CDC20. This complex can also phosphorylate MAD1L1.
Gene ID
9184
UniProt
O43684
Pathways
Maintenance of Protein Location
Recently viewed
(hide)