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IL-6 Receptor antibody
IL6R
Reactivity: Human, Mouse
WB, ELISA, IP
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-IL-6 Receptor Antibody
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Target
See all IL-6 Receptor (IL6R) Antibodies
IL-6 Receptor (IL6R)
(Interleukin 6 Receptor (IL6R))
Reactivity
All reactivities for IL-6 Receptor antibodies
Human, Mouse
Host
All hosts for IL-6 Receptor antibodies
Rabbit
Clonality
All clonalities for IL-6 Receptor antibodies
Polyclonal
Conjugate
All conjugates for IL-6 Receptor antibodies
This IL-6 Receptor antibody is un-conjugated
Application
All applications for IL-6 Receptor antibodies
Western Blotting (WB), ELISA, Immunoprecipitation (IP)
Immunogen
interleukin 6 receptor
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freeze / thaw cycles.
Storage
-20 °C
Expiry Date
12 months
Target Details for IL-6 Receptor
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Target
IL-6 Receptor (IL6R)
(Interleukin 6 Receptor (IL6R))
Alternative Name
IL6R (IL6R Products )
Synonyms
IL6R antibody, il-6ra antibody, CD126 antibody, IL-6R-1 antibody, IL-6RA antibody, IL6Q antibody, IL6RA antibody, IL6RQ antibody, gp80 antibody, IL6R1 antibody, Il6ra antibody, IL-6Ralpha antibody, IL-6R antibody, Il6r antibody, interleukin 6 receptor antibody, interleukin 6 receptor, alpha antibody, IL6R antibody, il6r antibody, Il6r antibody, Il6ra antibody
Background
Synonyms:CD126, gp80, IL 6 receptor subunit alpha, IL 6R 1, IL 6R alpha, IL 6R subunit alpha, IL 6RA, IL-6 R alpha, IL-6R, IL6RA, interleukin 6 receptor, Membrane glycoprotein 80 Background:Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis. Low concentration of a soluble form of IL6 receptor acts as an agonist of IL6 activity.
Molecular Weight
80 kDa
Gene ID
3570
UniProt
P08887
Pathways
JAK-STAT Signaling , Autophagy , Growth Factor Binding , Cancer Immune Checkpoints
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