PLSCR3 antibody

Catalog No. ABIN5704160

Product Details anti-PLSCR3 Antibody

Target: PLSCR3 (phospholipid Scramblase 3 (PLSCR3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLSCR3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Immunogen: phospholipid scramblase 3

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for PLSCR3

Target: PLSCR3 (phospholipid Scramblase 3 (PLSCR3))

Alternative Name: PLSCR3 (PLSCR3 Products)

Synonyms: 2210403O21Rik antibody, 2610037N06Rik antibody, ESTM3 antibody, X83310 antibody, Pls3 antibody, zgc:77051 antibody, phospholipid scramblase 3 antibody, phospholipid scramblase 3b antibody, PLSCR3 antibody, Plscr3 antibody, plscr3b antibody

Background: Synonyms: Background:May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages.

Gene ID: 57048

UniProt: Q9NRY6

Pathways: Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis