SF3B4 antibody

Catalog No. ABIN5704341

Product Details anti-SF3B4 Antibody

Target: SF3B4 (Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SF3B4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogen: splicing factor 3b, subunit 4, 49kDa

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

HeLa cells were subjected to SDS PAGE followed by western blot with FNab07780(SF3B4 antibody) at dilution of 1:500

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for SF3B4

Target: SF3B4 (Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))

Alternative Name: SF3B4 (SF3B4 Products)

Synonyms: chunp6902 antibody, fb36a04 antibody, wu:fb36a04 antibody, 49kDa antibody, SF3b49 antibody, SF3b50 antibody, Sap49 antibody, spx antibody, AFD1 antibody, Hsh49 antibody, SAP49 antibody, Splicing factor 3B subunit 4 antibody, splicing factor 3b, subunit 4 antibody, splicing factor 3b subunit 4 S homeolog antibody, splicing factor 3b subunit 4 antibody, sap-49 antibody, sf3b4 antibody, Sf3b4 antibody, sf3b4.S antibody, SF3B4 antibody

Background: Synonyms:SAP49 Background:Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence(BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. SF3B4 has been found in complex 'B' and 'C' as well. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.

Gene ID: 10262

UniProt: Q15427