SOX7 antibody

Catalog No. ABIN5704397

Product Details anti-SOX7 Antibody

Target: SOX7 (SRY (Sex Determining Region Y)-Box 7 (SOX7))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Immunogen: SRY (sex determining region Y)-box 7

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

COLO 320 cells were subjected to SDS PAGE followed by western blot with FNab08129( SOX7 Antibody) at dilution of 1:600

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for SOX7

Target: SOX7 (SRY (Sex Determining Region Y)-Box 7 (SOX7))

Alternative Name: SOX7 (SOX7 Products)

Synonyms: sox7-A antibody, xSox7 antibody, SRY-box 7 antibody, SRY (sex determining region Y)-box 7 antibody, SRY box 7 antibody, SRY-box 7 L homeolog antibody, SOX7 antibody, Sox7 antibody, sox7 antibody, sox7.L antibody

Background: Synonyms: Background:Binds to and activates the CDH5 promoter, hence plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium and blocks further differentiation into blood precursors(By similarity). May be required for the survival of both hematopoietic and endothelial precursors during specification(By similarity). Competes with GATA4 for binding and activation of the FGF3 promoter(By similarity). Represses Wnt/beta-catenin-stimulated transcription, probably by targeting CTNNB1 to proteasomal degradation. Binds the DNA sequence 5'-AACAAT-3'.

Gene ID: 83595

UniProt: Q9BT81

Pathways: Positive Regulation of Endopeptidase Activity