STEAP3 antibody

Catalog No. ABIN5704404

Product Details anti-STEAP3 Antibody

Target: STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STEAP3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Immunogen: STEAP family member 3

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

HepG2 cells were subjected to SDS PAGE followed by western blot with FNab08318(STEAP3 antibody) at dilution of 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for STEAP3

Target: STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

Alternative Name: STEAP3 (STEAP3 Products)

Synonyms: STEAP3 antibody, 1010001D01Rik antibody, Tsap6 antibody, pHyde antibody, AHMIO2 antibody, STMP3 antibody, TSAP6 antibody, dudlin-2 antibody, STEAP3 metalloreductase antibody, STEAP family member 3 antibody, STEAP3 antibody, steap3 antibody, Steap3 antibody

Background: Synonyms:TSAP6 Background:Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+). Can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. Uses NADP(+) as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.

Gene ID: 55240

UniProt: Q658P3

Pathways: Transition Metal Ion Homeostasis