UPF3B antibody
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- Target See all UPF3B Antibodies
- UPF3B (UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This UPF3B antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Immunogen
- UPF3 regulator of nonsense transcripts homolog B (yeast)
- Isotype
- IgG
- Top Product
- Discover our top product UPF3B Primary Antibody
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- Application Notes
- WB : 1:500-1:5000,IHC:1:20-1:200
- Comment
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Jurkat cells were subjected to SDS PAGE followed by western blot with FNab09272(UPF3B antibody) at dilution of 1:2000
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- UPF3B (UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B))
- Alternative Name
- UPF3B (UPF3B Products)
- Synonyms
- HUPF3B antibody, MRXS14 antibody, RENT3B antibody, UPF3X antibody, 5730594O13Rik antibody, AI317193 antibody, AW541158 antibody, RGD1560264 antibody, UPF3B, regulator of nonsense mediated mRNA decay antibody, UPF3 regulator of nonsense transcripts homolog B (yeast) antibody, UPF3B antibody, Upf3b antibody
- Background
- Synonyms:HUPF3B, hUpf3p X, MRXS14, RENT3B, UPF3B, UPF3X Background:Involved in nonsense-mediated decay(NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex(EJC) and serving as link between the EJC core and NMD machinery. Recruits UPF2 at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex(including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. In cooperation with UPF2 stimulates both ATPase and RNA helicase activities of UPF1. Binds spliced mRNA upstream of exon-exon junctions. In vitro, stimulates translation, the function is independent of association with UPF2 and components of the EJC core.
- Molecular Weight
- 51kDa
- Gene ID
- 65109
- UniProt
- Q9BZI7
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