MX1 antibody

Catalog No. ABIN5705684

Product Details anti-MX1 Antibody

Target: MX1 (Myxovirus Resistance Protein 1 (MX1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MX1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Immunogen: myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 ( Mouse )

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

mouse spleen tissue were subjected to SDS PAGE followed by western blot with FNab05450(MX1 antibody) at dilution of 1:300

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for MX1

Target: MX1 (Myxovirus Resistance Protein 1 (MX1))

Alternative Name: MX1 (MX1 Products)

Synonyms: IFI78 antibody, AI893580 antibody, Mx antibody, Mx-1 antibody, IFI-78K antibody, MX antibody, MxA antibody, Mx1-b antibody, Mx1B antibody, OGTPBP antibody, ONBP antibody, myxovirus (influenza virus) resistance 1 antibody, MX dynamin-like GTPase 1 antibody, MX dynamin like GTPase 1 antibody, Mx1 antibody, MX1 antibody

Background: Synonyms:IFI 78K, IFI78, Interferon induced protein p78, MX, MX1, MxA, Myxovirus resistance protein 1 Background:Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses. Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid. May also antagonize reoviridae and asfarviridae replication. Inhibits thogoto virus(THOV) replication by preventing the nuclear import of viral nucleocapsids. Inhibits La Crosse virus(LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress. Inhibits influenza A virus(IAV) replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles. Enhances ER stress-mediated cell death after influenza virus infection. May regulate the calcium channel activity of TRPCs.

Molecular Weight: 76 kDa

Gene ID: 4599

UniProt: P20591