EXD2 antibody
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- Target See all EXD2 products
- EXD2 (Exonuclease 3'-5' Domain Containing 2 (EXD2))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This EXD2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
- Immunogen
- exonuclease 3'-5' domain containing 2
- Isotype
- IgG
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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mouse lung tissue were subjected to SDS PAGE followed by western blot with FNab02890(EXD2 antibody) at dilution of 1:300
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- EXD2 (Exonuclease 3'-5' Domain Containing 2 (EXD2))
- Alternative Name
- EXD2 (EXD2 Products)
- Synonyms
- C14orf114 antibody, EXDL2 antibody, 4930539P14Rik antibody, C85658 antibody, Exdl2 antibody, RGD1311087 antibody, exd2-b antibody, exdl2 antibody, fi72h12 antibody, wu:fi72h12 antibody, zgc:175195 antibody, exd2 antibody, exd2-a antibody, exonuclease 3'-5' domain containing 2 antibody, exonuclease 3'-5' domain containing 2 b antibody, EXD2 antibody, Exd2 antibody, exd2.S antibody, exd2 antibody, exd2.L antibody
- Background
- Synonyms:C14orf114, Background:Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.
- Molecular Weight
- 56 kDa
- Gene ID
- 55218
- UniProt
- Q9NVH0
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