Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

AIM2 antibody (Absent in Melanoma 2) (C-Term) Primary Antibody

AIM2 Reactivity: Human IHC, ELISA, WB Host: Goat Polyclonal unconjugated
Catalog No. ABIN571131
$481.84
Plus shipping costs $45.00
100 μg
local_shipping Shipping to: United States
Delivery in 6 to 7 Business Days
  • Target
    AIM2
    Binding Specificity
    C-Term
    • 15
    • 12
    • 8
    • 8
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Reactivity
    Human
    • 84
    • 26
    • 20
    • 3
    • 3
    • 1
    Host
    Goat
    • 65
    • 12
    • 8
    Clonality
    Polyclonal
    • 76
    • 9
    Conjugate
    This AIM2 antibody is un-conjugated
    • 46
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Application
    Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
    • 66
    • 45
    • 25
    • 23
    • 20
    • 13
    • 13
    • 6
    • 5
    • 3
    • 2
    • 1
    Purpose
    AIM2
    Sequence
    GEKLQLTSGV HSTIK
    Predicted Reactivity
    Human
    Purification
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
    Grade
    Verified
    Immunogen
    Peptide with sequence C-GEKLQLTSGVHSTIK, from the C Terminus of the protein sequence according to NP_004824.1.
    Isotype
    IgG
  • Application Notes

    DS WB Results: Approx 50+55 kDa bands observed in lysates of Human WI-38 fibroblast after treatment with interferon beta (calculated MW of 39.0 kDa according to NP_004824.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Choubey et al., J Interferon Cytokine Res. 2010 Jun,30(6):371-80. PMID: 20187776). Recommended concentration: 1-3 μg/mL.

    DS IHC Results: In paraffin embedded Human Spleen shows nucleolar staining in some splenocytes. Recommended concentration, 4-6 μg/mL.

    Peptide ELISA: antibody detection limit dilution 1:8000.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Minimize freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
  • Target
    AIM2
    Alternative Name
    AIM2 (AIM2 Antibody Abstract)
    Synonyms
    AIM2, PYHIN4, Gm1313, Ifi210, absent in melanoma 2, AIM2, Aim2
    Background
    AIM2, absent in melanoma 2, PYHIN4
    Molecular Weight
    39.0kDa
    Gene ID
    9447
    NCBI Accession
    NP_004824
    Pathways
    Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
You are here:
help Support