FAK antibody (pTyr397)

Catalog No. ABIN594976

This Rabbit Polyclonal antibody specifically detects FAK in WB. It exhibits reactivity toward Human, Mouse, Rat, Chicken, Monkey, Zebrafish (Danio rerio), Xenopus laevis, Dog, Rabbit, Cow, Horse and Drosophila melanogaster.

Quick Overview for FAK antibody (pTyr397) (ABIN594976)

Target: FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

Reactivity: Human, Mouse, Rat, Chicken, Monkey, Zebrafish (Danio rerio), Xenopus laevis, Dog, Rabbit, Cow, Horse, Drosophila melanogaster

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAK antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FAK Antibody

Binding Specificity: pTyr397

Specificity: Recognizes human FAK when phosphorylated at tyrosine 397. Species cross-Reactivity: mouse, rat.

Purification: Immunoaffinity purified

Immunogen: Synthetic phosphopeptide corresponding to human FAK around the phosphorylation site of tyrosine 397 (D-D-YP-A-E).

Type of Immunogen: Synthetic phospho-peptide

Isotype: IgG

Application Details

Application Notes: Approved: WB (1:500 - 1:1000)

Usage: Suitable for use in Western blot: 1:500-1:1000.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS (without Mg2+, Ca2+),  pH 7.4, 150 mM sodium chloride, 0.02 % sodium azide, 50 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Aliquot to Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for at least 1 year.

Target Details for FAK

Target: FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

Alternative Name: FAK / Focal Adhesion Kinase

Background: Name/Gene ID: PTK2
Subfamily: Focal Adhesion Kinase
Family: Protein Kinase

Synonyms: PTK2, FADK, Fadk1, Focal adhesion kinase, FRNK, FADK 1, Focal adhesion kinase 1, FAK1, p125FAK, PPP1R71, Protein-tyrosine kinase 2, PTK2 protein tyrosine kinase 2, FAK, pp125 FA kinase, Pp125FAK

Gene ID: 5747

UniProt: Q05397

Pathways: Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling