Claudin 11 antibody

Catalog No. ABIN5956303

Product Details anti-Claudin 11 Antibody

Target: Claudin 11 (CLDN11)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 11 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Claudin 11,Claudin-11,CLD11,Cldn11,Oligodendrocyte transmembrane protein,Oligodendrocyte-specific protein,OSP,OTM

Purification: Affinity purification

Immunogen: Synthesized peptide derived from human Claudin 11

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000, ELISA 1:10000-20000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide,0.5 % BSA and 50 % glycerol  pH 7.4.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Claudin 11

Target: Claudin 11 (CLDN11)

Alternative Name: Claudin 11 (CLDN11 Products)

Synonyms: cldn11 antibody, fb97c11 antibody, wu:fb97c11 antibody, claudin-11 antibody, CLDN11 antibody, Claudin-11 antibody, DKFZp459H2322 antibody, OSP antibody, OTM antibody, Claudin11 antibody, Osp antibody, Otm antibody, claudin 11b antibody, claudin 11 antibody, cldn11b antibody, CLDN11 antibody, Cldn11 antibody

Background: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a major component of central nervous system (CNS) myelin and plays an important role in regulating proliferation and migration of oligodendrocytes. Mouse studies showed that the gene deficiency results in deafness and loss of the Sertoli cell epithelial phenotype in the testis.

Gene ID: 5010

UniProt: O75508

Pathways: Hepatitis C