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HDAC2 antibody (Ser394)
HDAC2
Reactivity: Human, Mouse, Rat, Monkey
WB, ELISA, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-HDAC2 Antibody
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Target
See all HDAC2 Antibodies
HDAC2
(Histone Deacetylase 2 (HDAC2))
Binding Specificity
All epitopes for HDAC2 antibodies
Ser394
Reactivity
All reactivities for HDAC2 antibodies
Human, Mouse, Rat, Monkey
Host
All hosts for HDAC2 antibodies
Rabbit
Clonality
All clonalities for HDAC2 antibodies
Polyclonal
Conjugate
All conjugates for HDAC2 antibodies
This HDAC2 antibody is un-conjugated
Application
All applications for HDAC2 antibodies
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificity
D10Wsu179e,HD 2,HD2,HDAC 2,Hdac2,HDAC2,Histone deacetylase 2 (HD2),Histone deacetylase 2,OTTHUMP00000017046,OTTHUMP00000227077,OTTHUMP00000227078,RPD3,transcriptional regulator homolog RPD3,YAF1,YY1 associated factor 1,YY1 transcription factor binding protein,Yy1bp
Purification
Affinity purification
Immunogen
Synthesized peptide derived from human HDAC2 around the non-phosphorylation site of Ser394.
Isotype
IgG
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Discover our top product HDAC2 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for HDAC2
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Target
HDAC2
(Histone Deacetylase 2 (HDAC2))
Alternative Name
HDAC2 (HDAC2 Products )
Synonyms
HD2 antibody, RPD3 antibody, YAF1 antibody, D10Wsu179e antibody, Yy1bp antibody, mRPD3 antibody, HISTONE DEACETYLASE antibody, T1N24.9 antibody, T1N24_9 antibody, histone deacetylase 2 antibody, histone deacetylase 2 antibody, histone deacetylase 2 S homeolog antibody, HDAC2 antibody, Hdac2 antibody, hdac2.S antibody, HDA2 antibody
Background
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.Forms transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR. Interacts in the late S-phase of DNA-replication with DNMT1 in the other transcriptional repressor complex composed of DNMT1, DMAP1, PCNA, CAF1. Deacetylates TSHZ3 and regulates its transcriptional repressor activity.
Molecular Weight
55kDa
Gene ID
3066
UniProt
Q92769
Pathways
Neurotrophin Signaling Pathway , Regulation of Muscle Cell Differentiation , Negative Regulation of intrinsic apoptotic Signaling , SARS-CoV-2 Protein Interactome , The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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